VRUS/ITMN…but what was the lag between the time Roche/ITMN saw these problems in the lab and the time it was revealed to the public?
The known toxicity problems with ITMN-191 could not possibly have predated VRUS’ interest in developing a purine nuke, which goes back at least 4.5 years to when VRUS licensed IP from Emory University and the University of Georgia in Feb 2006: