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Monday, 08/09/2010 1:26:06 PM

Monday, August 09, 2010 1:26:06 PM

Post# of 11606
When discussing the Roche partnership and possibilities I always like to re-read Halozyme's Chief Medical Officer's profile.....especially this part....

"From 2007 to 2009, Dr. Leff served at Roche as Vice President and Global Head, Inflammation Clinical Development and Disease Biology Leadership Team member. While at Roche, he helped lead the development of products for inflammation, including managing the clinical development department on a global basis for inflammation products in registration phase development, such as MabThera®/Rituxan®, ocrelizumab, and Actemra®. "

Dr. Jonathan Leff joined Halozyme in 2009 with extensive experience in clinical development and medical affairs, and a proven track record in pharmaceutical product development from early stage molecules through global filing, approval and launch. From 2007 to 2009, Dr. Leff served at Roche as Vice President and Global Head, Inflammation Clinical Development and Disease Biology Leadership Team member. While at Roche, he helped lead the development of products for inflammation, including managing the clinical development department on a global basis for inflammation products in registration phase development, such as MabThera®/Rituxan®, ocrelizumab, and Actemra®.

From 2002 to 2007, Dr. Leff was at Amgen Inc., where he served most recently as Vice President, North American Medical Affairs. His responsibilities included leadership of a department of 500 people, and the oversight of 5 therapeutic areas, 8 marketed products, and 4 late stage pipeline products, which involved the support and growth of 5 blockbuster brands: Neupogen®, Neulasta®, Epogen®, Aranesp®, and Enbrel®. In his prior role at Amgen, Dr. Leff was Senior Medical Director and Department Head of Osteoporosis Research, where he was responsible for conducting Phase 2 and 3 osteoporosis clinical trials for denosumab in over 10,000 patients, including a 7,800 patient fracture study. From 1994 to 2002, Dr. Leff was at Merck & Co., where he performed Phase 1 through Phase 4 clinical research studies for Singulair®, a leukotriene receptor antagonist, which resulted in a global filing and regulatory approval. From 1990 to 1994, Dr. Leff was a faculty member in the Pulmonary Division of the University of Colorado School of Medicine, with responsibilities for patient care, teaching, and basic research. Dr. Leff is board certified in Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. He received his B.A. in chemistry and M.D. from the University of Pennsylvania
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