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Re: turtlepower post# 100683

Wednesday, 08/04/2010 2:36:22 PM

Wednesday, August 04, 2010 2:36:22 PM

Post# of 257268

Teleprevir had some anemia issues in the 8-week arm.

A key distinction is that, according to VRTX, EPO was not permitted in the protocols of the ADVANCE and PROVE-3 studies.

discontinuations due to AE's when compared to the control group appears to be worse for Telaprevir than for Boceprevir.

The exclusion of EPO, which made it more difficult to keep Telaprevir patients with anemia enrolled in the trials, renders the comparison of discontinuation rates problematic.

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