Avid Bioservices Inc (CDMO)

[co3aii]

The Phase I is used to see basically that the new drug has no or manageable side effects, dosage, and is less dangerous in effect than the disease it is trying to cure. Once into Phase II any trial is subject to being halted if unexpected safety issues turn up which were not evident in Phase I, same too for Phase III. It is less likely that deleterious side effects will show up in II and III but given the wider population being tested and the varied genetics of the subjects it is something that needs to be looked out for. Of course II and III are efficacy trials with strict controls and if the trial indicates that the drug is not as efficacious as originally thought the trial will be halted.