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Re: mcbio post# 97894

Friday, 06/25/2010 6:44:38 PM

Friday, June 25, 2010 6:44:38 PM

Post# of 257302
Yes, I should have been clearer - obviously the FDA is concerned about preclinical signals of any compound under review. But in this case, we are talking about a signal from a knockout animal model. So that raises only a theoretical concern that I don't think the FDA would normally concern itself with.

But it does make me personally more cautious about the pathway in the long term.

Peter

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