I'd be careful chasing isme and ezto. I think both are heavily diluted. Just my .02, but when I first dd'ed ezto, I called a broker friend regarding the "e" a few weeks ago. He has friends at OTC and said the issue was shares exceeding authorized, then the amended 10Q was filed showing authorized increase to 400 million and blank check preffered.
ISME, I have traded several times now mid .01's to mid .02's but it hits a wall around .025 and then sinks, which tells me there is always a seller waiting at that level with lots of shares. Same thing happens to ezto at .051.
Just a caution, ok to swing trade, but don't chase them. Charts mean nothing if there's dilution.
Buzz