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Re: mcbio post# 97103

Thursday, 06/10/2010 8:13:47 PM

Thursday, June 10, 2010 8:13:47 PM

Post# of 257264

Does the long half-life for IDX320 potentially raise the same concerns for you as those of ACH-1625 (#msg-50215366 )?

No, because 26 hours is not that long—it’s just about perfect for qD dosing. ACH-1625, on the other hand, has a half-life of several days, which is suboptimal for an oral drug.

p.s. I had a feeling you would bring up ACH-1625 :- )


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