<<It is impractical to consider retreatments more often than monthly, IMHO.>>
I'm not sure I would agree with this, at least from the patient's point of view. The small sample I have of people with severe AMD (one person!) would happily submit to weekly or bi-weekly IVs to improve his sight. And this very point may be why Levitt seems so interested now in 10mg and sub-q.
Obviously there may be safety and cost issues weighing against this frequency.
All your points are excellent food for thought, as always. Thanks for taking the time.