Saturday, May 29, 2010 6:45:46 PM
MNTA European Patent Applications Update for RMF - Plus MNTA Overview of their Patent Estate -
1.{NEW} CHARACTERIZATION OF N-GLYCANS USING EXOGLYCOSIDASES
Inventor: PARSONS IAN CHRISTOPHER [US] ; BULIK DOROTA A [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
Abstract: The present disclosure provides methods for analyzing structure and/or composition of N-glycans. Such methods often involve digestion of N-glycans with multiple exoglycosidases. In some embodiments, N-glycans are digested with multiple exoglycosidases simultaneously. In some embodiments, N-glycans are digested with multiple exoglycosidases sequentially. In some embodiments, methods in accordance with the present disclosure involve comparison of cleavage products of N-glycans that have been digested with multiple exoglycosidases simultaneously to N-glycans that have been digested with multiple exoglycosidases sequentially.
2010-05-27
2.{NEW} IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1
Inventor: IYER MANI S [US] ; BAUER CORINNE [US] (+1) Applicant: MOMENTA PHARMACEUTICALS INC
Abstract: The presently disclosed subject matter provides a novel method for preparing copolymer- 1. In one embodiment, a mixture of N-carboxyanhydrides (NCAs) comprising alanine, protected-glutamic acid, protected lysine, and tyrosine, and wherein glutamic acid includes a benzyl or methoxy protecting group and lysine includes a cyclic imide or Boc protecting group are treated with a polymerization initiator to initiate polymerization of the mixture of N-carboxyanhydrides and to thereby synthesize a protected copolymer- 1. The protected copolymer- 1 can then be treated with deprotecting groups and/or depolymerized to obtain a copolymer- 1 having a desired molecular weight.
2010-05-07
3.{NEW} Non-anticoagulant polysaccharide compositions
Inventor: SUNDARAM MALLIK ; ROY SUCHARITA (+1)
Applicant: MOMENTA PHARMACEUTICALS INC
Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
2009-05-07
4.DEFINED GLYCOPROTEIN PRODUCTS AND RELATED METHODS Abstract - The invention provides methods, databases and systems for making glycoprotein products having defined properties
Inventor: VENKATARAMAN GANESH [US] ; COLLINS BRIAN EDWARD Applicant: MOMENTA PHARMACEUTICALS INC [US]
2010-05-06
5.COPOLYMER ASSAY
Inventor: D ALESSANDRO JOSEPHINE S [US] ; KISHIMOTO TAKASHI KEI Applicant: MOMENTA PHARMACEUTICALS INC [US]
2010-04-14
6.EVALUATING HEPARIN PREPARATIONS FOR PHARMACEUTICAL USE
Inventor: SCHRIER DAVID [US] ; GUNAY NUR SIBEL [US] Applicant: MOMENTA PHARMACEUTICALS INC [US] ; SCHRIER DAVID [US]
2010-03-11
7.SACCHARIDE STRUCTURES AND METHODS OF MAKING AND USING SUCH STRUCTURES
Inventor: ROY SUCHARITA [US] ; KISHIMOTO TAKASHI KEI [US] Applicant: MOMENTA PHARMACEUTICALS INC [US] ; ROY SUCHARITA [US]
2009-12-23
8.MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS
Inventor: PARSONS IAN CHRISTOPHER [US] ; ZHENG TING [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
2009-12-30
9.METHODS RELATED TO CELL SURFACE GLYCOSYLATION
Inventor: COLLINS BRIAN EDWARD [US] ; BOSQUES CARLOS J [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
2009-12-23
http://v3.espacenet.com/searchResults?locale=en_V3&query=(txt+%3D+momenta)+and+(txt+%3D+pharmaceuticals)&compact=false&DB=EPODOC&submitted=true
___________________________________________
PATENTS
Over 100 patents give Momenta a strong proprietary position
Momenta possesses a strong intellectual property position around our characterization platform. We license or own a total of over 100 patents and patent applications. Our patent portfolio includes claims covering:
•methods and technologies for characterizing sugars;
•the use of certain enzymes and reagents that specifically recognize polysaccharides in the characterization of sugars;
•methods and technologies for chemical and metabolic synthesis of sugars;
•the composition of matter of certain novel low-molecular-weight herapins (LMWHs), including M118, and heparinase variants;
•methods to produce and identify sugars associated with glycoproteins;
•methods to analyze and monitor glycoprotein profiles for purposes associated with the diagnosis, staging, prognosis and monitoring of cancer; and
•methods for the in vivo non-invasive delivery of sugars.
We also rely on trade secrets, know-how, continuing technological innovation and in-licensing opportunities to develop and maintain our proprietary position
http://www.momentapharma.com/technology/patents.html
1.{NEW} CHARACTERIZATION OF N-GLYCANS USING EXOGLYCOSIDASES
Inventor: PARSONS IAN CHRISTOPHER [US] ; BULIK DOROTA A [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
Abstract: The present disclosure provides methods for analyzing structure and/or composition of N-glycans. Such methods often involve digestion of N-glycans with multiple exoglycosidases. In some embodiments, N-glycans are digested with multiple exoglycosidases simultaneously. In some embodiments, N-glycans are digested with multiple exoglycosidases sequentially. In some embodiments, methods in accordance with the present disclosure involve comparison of cleavage products of N-glycans that have been digested with multiple exoglycosidases simultaneously to N-glycans that have been digested with multiple exoglycosidases sequentially.
2010-05-27
2.{NEW} IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1
Inventor: IYER MANI S [US] ; BAUER CORINNE [US] (+1) Applicant: MOMENTA PHARMACEUTICALS INC
Abstract: The presently disclosed subject matter provides a novel method for preparing copolymer- 1. In one embodiment, a mixture of N-carboxyanhydrides (NCAs) comprising alanine, protected-glutamic acid, protected lysine, and tyrosine, and wherein glutamic acid includes a benzyl or methoxy protecting group and lysine includes a cyclic imide or Boc protecting group are treated with a polymerization initiator to initiate polymerization of the mixture of N-carboxyanhydrides and to thereby synthesize a protected copolymer- 1. The protected copolymer- 1 can then be treated with deprotecting groups and/or depolymerized to obtain a copolymer- 1 having a desired molecular weight.
2010-05-07
3.{NEW} Non-anticoagulant polysaccharide compositions
Inventor: SUNDARAM MALLIK ; ROY SUCHARITA (+1)
Applicant: MOMENTA PHARMACEUTICALS INC
Abstract: Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.
2009-05-07
4.DEFINED GLYCOPROTEIN PRODUCTS AND RELATED METHODS Abstract - The invention provides methods, databases and systems for making glycoprotein products having defined properties
Inventor: VENKATARAMAN GANESH [US] ; COLLINS BRIAN EDWARD Applicant: MOMENTA PHARMACEUTICALS INC [US]
2010-05-06
5.COPOLYMER ASSAY
Inventor: D ALESSANDRO JOSEPHINE S [US] ; KISHIMOTO TAKASHI KEI Applicant: MOMENTA PHARMACEUTICALS INC [US]
2010-04-14
6.EVALUATING HEPARIN PREPARATIONS FOR PHARMACEUTICAL USE
Inventor: SCHRIER DAVID [US] ; GUNAY NUR SIBEL [US] Applicant: MOMENTA PHARMACEUTICALS INC [US] ; SCHRIER DAVID [US]
2010-03-11
7.SACCHARIDE STRUCTURES AND METHODS OF MAKING AND USING SUCH STRUCTURES
Inventor: ROY SUCHARITA [US] ; KISHIMOTO TAKASHI KEI [US] Applicant: MOMENTA PHARMACEUTICALS INC [US] ; ROY SUCHARITA [US]
2009-12-23
8.MULTI-DIMENSIONAL CHROMATOGRAPHIC METHODS FOR SEPARATING N-GLYCANS
Inventor: PARSONS IAN CHRISTOPHER [US] ; ZHENG TING [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
2009-12-30
9.METHODS RELATED TO CELL SURFACE GLYCOSYLATION
Inventor: COLLINS BRIAN EDWARD [US] ; BOSQUES CARLOS J [US] Applicant: MOMENTA PHARMACEUTICALS INC [US]
2009-12-23
http://v3.espacenet.com/searchResults?locale=en_V3&query=(txt+%3D+momenta)+and+(txt+%3D+pharmaceuticals)&compact=false&DB=EPODOC&submitted=true
___________________________________________
PATENTS
Over 100 patents give Momenta a strong proprietary position
Momenta possesses a strong intellectual property position around our characterization platform. We license or own a total of over 100 patents and patent applications. Our patent portfolio includes claims covering:
•methods and technologies for characterizing sugars;
•the use of certain enzymes and reagents that specifically recognize polysaccharides in the characterization of sugars;
•methods and technologies for chemical and metabolic synthesis of sugars;
•the composition of matter of certain novel low-molecular-weight herapins (LMWHs), including M118, and heparinase variants;
•methods to produce and identify sugars associated with glycoproteins;
•methods to analyze and monitor glycoprotein profiles for purposes associated with the diagnosis, staging, prognosis and monitoring of cancer; and
•methods for the in vivo non-invasive delivery of sugars.
We also rely on trade secrets, know-how, continuing technological innovation and in-licensing opportunities to develop and maintain our proprietary position
http://www.momentapharma.com/technology/patents.html
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