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Re: rkrw post# 95859

Sunday, 05/16/2010 11:19:01 PM

Sunday, May 16, 2010 11:19:01 PM

Post# of 257264

I think that's very naive!

Why? How are telaprevir and boceprevir going to successfully fend off competitive HCV PIs with potentially significant advantages in dosing, potency, safety, and pan-genotypic coverage? I realize the 2nd and 3rd gen HCV PIs still have a ways to go in the clinic to realize these advantages, but they represent significant threats to telaprevir and boceprevir in the not-too-distant future.

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