PYMX part 2... From the horse's (company's) mouth on your #2 question:
"The natural defensins don't fail. In humans they are used as a barrier and not as a systemic response. The barrier works well until bacteria get inside the body and we can't mount a systemic defense against them. Below are two papers which include more information. "
Zasloff et al, Nature, v415, pg 389-395. January 24, 2002
Tossi et al, Biopolymers, v55, pg 4-30. July 2000
Unless otherwise indicated, this is the personal viewpoint of David
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