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Re: DewDiligence post# 93782

Thursday, 04/08/2010 1:01:46 AM

Thursday, April 08, 2010 1:01:46 AM

Post# of 257253
Re: MNTA/M118

The primary end point occurred in 31.1% of patients randomized to UFH and in 22.7%, 28.3%, and 30.1% of patients randomized to M118 50, 75, and 100 IU/kg, respectively.

It appears that there is a pretty clear dose-response relationship with respect to M118. Is it expected that MNTA or, more likely, a partner will test M118 at doses above the 100 IU/kg level in an upcoming Phase 2b trial to see if M118 can produce even better results?

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