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Re: DewDiligence post# 93563

Friday, 04/02/2010 10:28:49 AM

Friday, April 02, 2010 10:28:49 AM

Post# of 257253
If a patient fails an anti-TNF agent (there are 5 in the market), doc can either put him on a different anti-TNF agent or switch to a non anti-TNF agent (Actemra, Orencia, Rituxan). Among the latter class (Simponi and Cimzia mentioned in the Sermo Event Report are both anti-TNFs), Orencia has the better efficacy/safety profile and a broader label. BMY also conducts a phase III head-to-head vs. Humira trial to compete in 1st line RA:

http://clinicaltrials.gov/ct2/show/NCT00929864?term=NCT00929864&rank=1

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