Yeah...simply having the trait is a walk in the park-just ask the football and basketball players who have succumbed to heat and exercise related deaths who carried the trait---and the rest of these non-sickly people...
People with the sickle cell trait have one copy of the sickle cell gene. Two copies of the sickle cell gene yield the full sickle cell disease. Effects of the sickle cell trait vary depending on the carrier but are generally rare and usually mild and manageable.
Urinary Tract Infection in Women 1. Women with the sickle cell trait have a higher risk of urinary tract infection than female noncarriers. Exercise-Related Death 2. Men and women with the sickle cell trait are more likely to experience unexpected exercise-related deaths. Splenic Infarction 3. When carriers of the sickle cell trait are exposed to altitude-induced hypoxia (oxygen deficiency), they have a greater risk of having a splenic infarction (death of spleen tissue) due to the irregular shape of the red blood cells. Hematuria 4. Sickle cell trait carriers are more likely to experience hematuria, or blood in the urine. Heat Stroke 5. Heat stroke, or exertional heat illness, has a higher occurrence among carriers of the sickle cell trait as opposed to noncarriers.