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Re: DewDiligence post# 5641

Sunday, 12/12/2004 11:23:59 PM

Sunday, December 12, 2004 11:23:59 PM

Post# of 257628
Cortex is still an unknown small biotech to the media...

but I think 2005 is the year this changes.

When Cortex/Ampakines are mentioned in the press it has almost always been for memory indications, and the articles continue to mention CX-516 which is dead as far as future development - all of Cortex's upcoming Phase II's and pilot trials will be using CX-717.

Parkinson's is one indication I can forgive them for for not mentioning Ampakines. Lilly had a PD/Ampakine Phase II that recently terminated due to toxicity issues, and it looks like it may take at least a year (very rough estimate by Cortex's CEO, Dr. Stoll) for Cortex to develop a high impact Ampakine that gets around the toxicity issues.

In the meantime Cortex is the only company with a safe low impact and (so far) effective Ampakine in CX-717. If the Sleep Dep Phase II's planned for early next year plus the pilot studies in PD, ADHD, and AD show promise and result in a BP deal, then the press will discover Ampakines... Aiming4.

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