Lupron Depot’s dose-vs-duration relationship is surprisingly linear: http://finance.yahoo.com/news/Abbott-Seeks-FDA-Approval-of-prnews-3056061455.html?x=0&.v=1 With the new approval, the doses/durations in use are: • 7.5mg for one month • 22.5mg for three months • 30mg for four months • 45mg for six months An older 3.75mg monthly dose is apparently no longer used.