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Re: biopearl post# 91828

Friday, 03/05/2010 5:58:37 PM

Friday, March 05, 2010 5:58:37 PM

Post# of 257257
re ipilimumab

These are very impressive pictures



yes but don't get carried away - other companies have had CRs in early trials of melanoma, and i don;t need to remind you of the success rate historicaly in this indication

Any sense for the % of patients who respond to therapy?



about 10%. i would suggest you check for old abstracts for both CTL4 antibodies (pfizer has one in development) - we're not talking huge response rates here (but if they can get druable responses and CRs then that will be quite meaningful even with a modest overal RR)





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