Davidal, Neuro, et. al.,
What do you think of this post (from Dew's I-hub board)?
Exalgo... A clinician's take...
Tiny CRXX's recent FDA approval of its time release analgesic Exalgo is being yawned off by the market. The PPS dwindled today into the low 1.30s.
As a practicing plastic surgeon I assure everybody that I will be contacting the company to find out how soon I can start prescribing Exalgo. Lay people sometimes do not appreciate the importance of convenience in clinical medicine.
Several decades ago I was a surgical resident at Beth Israel in Boston. At that time we lacked many of the electronic monotering equipmentthat exist today. Most physicians who worked in critical care understood how important it was to monitor central venous pressure. Non the less most hospital CC units did not place central pressure lines because of the techical difficulty of placing the lines and the even harder job of maintaining them..
Today when you give post op patients PO analgesics, their usual duration is about 3 hours.. In a hospital setting this creates more work for the floor nurses, if you send the patient home, short acting analgesics are more likely to be abused..patients frequently double and triple their doses, which even in cases where there is no serious problem, means the patient is calling the office one or two days after surgery and asking for more meds. Short acting analgesics also "bounce" as the blood levels drop creating a mini withdrawl...
In short I think CRXX's time release painkiller will be a big deal in clinical medicine...
Bladerunner