Primary endpt might be stacked in their favor. Co Primary endpoint is adenocarcinoma subset and at a fair bit > 1/2 of enrolled. <A HREF="http://hcp.iressa.com/article/504498.aspx" target="_blank">http://hcp.iressa.com/article/504498.aspx</A> Isn't adeno where most nonsmokers are? This is where tarceva did best.