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Re: DewDiligence post# 89523

Saturday, 01/23/2010 11:01:07 PM

Saturday, January 23, 2010 11:01:07 PM

Post# of 257253
Conatus - HCV

No patients in the trial receive interferon, and the variable between the two trial arms is not the experimental drug, CTS-1027, as one might, but rather is ribavirin. I.e. one of the two trial arms is CTS-1027 monotherapy for 24 weeks!



Odder is that the trial to which you are referring is 1027 vs 1027 plus rib despite the fact that in a different trial for the same drug they note:

a) 1027 is not an antiviral and has minimal efficacy by itself

b) 1027 is hypothesized to be a potentiator of IFN

Just kinda odd what combo's they are trying.

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