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Re: brainlessone post# 4651

Sunday, 11/07/2004 9:09:45 PM

Sunday, November 07, 2004 9:09:45 PM

Post# of 257660
>> in your first message [#4615] you said .0125 for each OR .05 for all. which is really meant or both? <<

I just reread #4615 and my language was indeed ambiguous. Mea culpa.

What QLTI needs to show for a successful VIO trial is p<0.0125 in any of the four endpoints. However, they have already missed the 3-line and 6-line endpoints at one year, leaving only two remaining shots on goal: the 3-line and 6-line endpoints at two years.

The chance of QLTI’s hitting either of the two-year endpoints with p<0.0125 is not good, in my opinion.

Thank you for bringing the ambiguity in #4615 to my attention. Regards, Dew


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