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Re: ThomasS post# 87800

Friday, 12/18/2009 6:40:52 PM

Friday, December 18, 2009 6:40:52 PM

Post# of 257580
The word biosimilar does not convey any nuance in this context, IMO. We cannot say with assurance whether M178 would ever have been approvable as a substitutable FoB, but NVS may have concluded that the possibility was remote.

If the branded counterpart of M178 had been a bona fide blockbuster, it might still have been worth NVS/MNTA’s time and money to develop a non-substitutable FoB. However, we can surmise that the branded counterpart of M178 is not a blockbuster from the small size ($15M) of the milestone payments attributable to M178 in NVS/MNTA’s 2006 collaboration.


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