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Re: iwfal post# 85636

Sunday, 11/01/2009 7:29:05 PM

Sunday, November 01, 2009 7:29:05 PM

Post# of 252497
It still shows hints of many of the toxicities seen for Amiodarone - more in fact than Dronedarone (another Amiodarone redo - but with lesser efficacy than Amiodarone). (Note the word 'hints' because from the data released so far it is hard to tell anything other than that it probably still has some kind of tox for thyroid and liver - both of which are significant for Amiodarone, although I can't, for instance, find median blood data for such Amiodarone SAEs) In contrast Vernakalant(sp?) appears to have fewer side effects.

Not a comment, just a question. You are saying there is probably tox in the liver and thyroid based on the data presented. What data that was presented gives you that idea?

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