Biotech Values

[DewDiligence]

Re: VRTX C208 study / Pegasys vs Pegintron

Is the RVR difference and duration between the PEG's something observed in other studies as well?

Although it’s been known anecdotally that Pegasys is the better drug (it now has about 70% of the market), there has been a dearth of studies comparing Pegasys and Pegintron in a scientifically rigorous manner. It’s a curious aspect of drug development that it required the advent of a direct antiviral such as Telaprevir to finally demonstrate that Pegasys works better.