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Re: Justa Werkenstiff post# 306145

Wednesday, 10/06/2004 11:53:53 AM

Wednesday, October 06, 2004 11:53:53 AM

Post# of 704047
I rather doubt that DNA rituxan will be at all comparable to either Chiron flu vaccine or Merck Vioxx.

The latter two were legitimate catastrophes, Vioxx has unacceptable side effects, is off the market, and merck is out a few billion USD in revenue.

Chiron screwed up royally on some routine manufacturing process, got their plant shut down, lost 40 million flu doses of revenue, looks like a total idiot, and the rest of the world will be pissed all winter.

The subpoena by the penn attorney general is presented without details so we have to guess. This however, isn't the FDA or the US attorney general who generally handle global matters of interstate commerce.

Rituxan is a low toxicity, targeted cancer therapy for NHL that is generally regarded as safe for what it is (an onc drug) and effective. If they withdrew Rituxan right now, a few tens of thousands of NHL patients would start dying over the next few months. Won't happen.
My best guess is that DNA is being targeted for pricing or marketing. They are known for aggressive marketing and have been caught at it before. And Rituxan like all new age biotech drugs is expensive. Wait and see but I don't see another Merck or Chiron in this.

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