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MNTA EU Patent Applications w/Abstracts -

For further information, select Description in each -

1. METHODS OF MAKING LOW MOLECULAR WEIGHT HEPARIN COMPOSITIONS 2009-08-27
Methods of making LMWH compositions are provided to provide the LMWH compositions at a yield of at least about 10%

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090827&CC=WO&NR=2009105522A1&KC=A1

2. METHODS OF MAKING GLYCOMOLECULES WITH ENHANCED ACTIVITIES AND USES THEREOF 2009-08-13
Methods to rapidly produce and identify polysaccharides, and other sugar structures, having enhanced activities, have been developed. The methods include producing a molecule, e.g., a therapeutic molecule, which includes a first, non-saccharide moiety (e.g., a protein, polypeptide, peptide, amino acid or lipid) and a second, polysaccharide, moiety. The method includes: determining the chemical composition and structure of all or a portion of the second moiety, modifying the structure of the second moiety to provide a modified second moiety, and evaluating or screening the molecule having the modified second moiety, e.g., for a biological activity or other chemical or physical property. In some embodiments, the step of determining the chemical structure and composition of the second moiety includes a comparison of one or more properties of the second moiety with a database, e.g., a database which correlates such one or more properties with structure or function of a polysaccharide.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090813&CC=US&NR=2009203550A1&KC=A1

3. NON-ANTICOAGULANT POLYSACCHARIDE COMPOSITIONS 2009-05-07
Preparations of polysaccharides lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090507&CC=WO&NR=2009059284A2&KC=A2

4. NON-ANTICOAGULANT POLYSACCHARIDE COMPOSITIONS 2009-05-07
Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090507&CC=WO&NR=2009059283A1&KC=A1

5. IMPROVED PROCESS FOR THE PREPARATION OF COPOLYMER-1 2008-01-10
The presently disclosed subject matter provides a novel method for prepar ing copolymer- 1. In one embodiment, a mixture of N-carboxyanhydrides (NCAs) comprising alanine, protected-glutamic acid, protected lysine, and tyrosine , and wherein glutamic acid includes a benzyl or methoxy protecting group an d lysine includes a cyclic imide or Boc protecting group are treated with a polymerization initiator to initiate polymerization of the mixture of N-carb oxyanhydrides and to thereby synthesize a protected copolymer- 1. The protec ted copolymer- 1 can then be treated with deprotecting groups and/or depolym erized to obtain a copolymer- 1 having a desired molecular weight.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20080110&CC=CA&NR=2656573A1&KC=A1

6. Analysis of sulfated polysaccharides 2009-03-19
The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090319&CC=AU&NR=2009200769A1&KC=A1

7. LOW MOLECULAR WEIGHT HEPARIN COMPOSITION AND USES THEREOF
2007-12-06
Preparations of low molecular weight heparins (LMWHs) having improved pro perties, e.g., properties that provide a clinical advantage, are provided he rein. Methods of making and using such preparations as well as methods of an alyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20071206&CC=CA&NR=2652205A1&KC=A1

8. ANALYSIS OF SULFATED POLYSACCHARIDES 2009-03-05
The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090305&CC=US&NR=2009061411A1&KC=A1

9. METHODS AND APPARATUS FOR CHARACTERIZING POLYMERIC MIXTURES 2009-02-12
The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20090212&CC=US&NR=2009043513A1&KC=A1

10. COPOLYMER ASSAY 2008-12-24
The present invention provides methods and compositions for evaluating one or more properties of an amino acid copolymer.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20081224&CC=WO&NR=2008157697A2&KC=A2

Addendum - Info regarding PCT Patent Applications from apljack
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