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Re: drbio45 post# 84087

Thursday, 09/24/2009 10:27:16 PM

Thursday, September 24, 2009 10:27:16 PM

Post# of 257443
Dr. Bio, Chemgenex omecataxine is not a very good drug and I believe it's questionable whether it will be approved in CML. This compound is a gimmick. Any chemo will do the same thing with t3151 because it's non specific and hits everything. Citing an 80% response rate is deceptive since the complete cytogenetic response rate has only been 20% and not durable. For chronic phase patients 70% had a grade 3-4 toxicity with only a 10% complete cytogenetic response and just 6 months duration. But don't believe me. Wait for the briefing documents come out.

As far as your questions, the trial started in January. And even if approved i believe it will have minimal if any bearing on enrolling clinical studies for t315i patients.

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