Biotech Values

[mcbio]

Re: VRUS PSI-7851 data

Preliminary Antiviral Response Observed Following PSI-7851 Administered as Monotherapy for 3 Days
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Dose N Mean Change in HCV RNA at Day 3
(Log(10))
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50mg QD 8 -0.49
100mg QD 8 -0.61
200mg QD 8 -1.01
Placebo 6 -0.03
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I totally missed this release on Friday given that it was at 7am. Thanks for posting.

So, if we compare the 100mg qd dose to that of IDX-184, IDX-184 was actually more potent, given a -0.74 mean decrease vs. a -0.61 mean decrease for PSI-7851. I think the bottom line is that IDIX needs to consider a 200mg qd dose in the next trial.