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Re: drbio45 post# 80401

Friday, 07/03/2009 4:15:32 AM

Friday, July 03, 2009 4:15:32 AM

Post# of 252713
Two points on Multaq:

1. In the DIONOSYS (head-to-head vs Amiodarone) trial - Multaq showed to be less effective at suppressing AF but safer.
2. Multaq is contraindicated in patients with severe heart failure (class IV and II-III). It can be used in patients with AF/AFL and no or stable heart failure.

So, Multaq is likely to compete and in time replace Amiodarone because of the safety advantages, imo.
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