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Re: DewDiligence post# 80341

Wednesday, 07/01/2009 9:44:53 PM

Wednesday, July 01, 2009 9:44:53 PM

Post# of 257253
CRP and heart disease - is CRP causitive or downstream or on a parallel stream or ...

Anyway, he said, it does not matter because the real issue is inflammation. CRP goes along with inflammation, and it is inflammation that is likely to be causing heart disease, Dr. Ridker said



FWIW I agree that the above quote is probably correct. That CRP probably isn't causitive per se, but that it is correlated with a causitive (inflammatory) path that is distinct from cholesterol. The point of disagreement within the scientific community isn't about CRP causation, but whether inflammation is a separate causation path potentially separately benefitted by statins. And CRP is a reliable proxy for that path.

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