Correction to the portion of #msg-38705594 you quoted, where the word not was accidentally omitted—the corrected sentence is as follows:
The problem with this approach to treating cancer is that the anticoagulation cascade does not have a lot of margin for error; hence, it will be hard for PCYC (or anyone else) to find a dose that is high enough to have anti-cancer efficacy without also causing severe bleeding…
I presume that you read the original sentence correctly by implicitly inserting the word not without even realizing you were doing it :- )
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”