Biotech Values

[genisi]

VPHM re Cinryze label expansion for self-administration:

First, (for those who didn't read the SI thread), we differ in our views regarding the commercial benefit: I do think that self-administration results in better compliance and will have positive effect on sales. My point is: before the revised label patients had to visit the clinic every three to four days, in an effort to prevent attacks (prophylaxis). Now the label allows self-administration so they can do it at home - independently, and save a lot of time and hassle.

On how to administer the drug:

Having an installed IV port does increased the risk of infection but implanting it under the skin helps reducing infection, and if the patient is taking routine disinfect measures, and being given antibiotics before and after dental work, the risk for infection is very low.
An implanted port is not absolutely essential for HAE patient who is on prophylaxis treatment, but it requires very little daily care, makes administration easier and less discomfort and is a good idea when maintaining home-based therapy. The decision is of course individual, but I personally would prefer a port over a needle, if I had to choose.