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Re: DewDiligence post# 79083

Friday, 06/05/2009 7:00:49 AM

Friday, June 05, 2009 7:00:49 AM

Post# of 257580
Another worry is - rash incidence and severity with longer dosing might worsen. While anti-viral activity at 400mg BID will probably have strong efficacy, not sure if rash could be manageable. ANDS thinks, based on PK/PD analysis that loading dose followed by reduced doses can do the trick but ANA598 chances to be successfully developed don't look too good for now.

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