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Re: zebra4o1 post# 3166

Friday, 08/13/2004 11:23:27 AM

Friday, August 13, 2004 11:23:27 AM

Post# of 257259
>> Is this Avastin warning serious, or a non-event? <<

Somewhere in between, IMHO. I don't think the warning will have a huge lasting effect on sales, but it may impede off-label use, particularly in the second-line colorectal setting for patients who already received Avastin the first line.

According to DNA, off-label use outside of colorectal cancer makes up about 5% of Avastin sales, and these sales may be affected too.

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