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Re: dewophile post# 78186

Wednesday, 05/20/2009 12:07:25 PM

Wednesday, May 20, 2009 12:07:25 PM

Post# of 257268
In general, I don't think anyone expects biosimilars to behave like conventional oral solid dose generics and capture 90% of the market quickly following launch. A key question imo is - how willing clinicians and payers are to use a cheaper biosimilar. This is influenced by many issues: type of treatment market, critical care or chronic, dosing (like with Avonex vs. Rebif), device of administration (as with GH biosimilars which have only made a smallish impact - less than 5% of market share), meaningful clinical or label differentiation to the brands (recall that even with no such differences Dynepo was a failure).

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