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Re: mcbio post# 77985

Sunday, 05/17/2009 3:00:09 AM

Sunday, May 17, 2009 3:00:09 AM

Post# of 257268
VRUS R7128 preclinical tox

While information is incomplete, (for example was the tox related to specific metabolite which is metabolized more extensively in monkeys), I think that since the monkey studies did not prevent the start of phase 2b trials designed with up to 1,000mg BID, I am cautiously optimistic about this.
On NOAEL, please see my reply to dewo.

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