iHub’s Greatest Hits [Additions: blog from The Atlantic on why US healthcare costs so much; new section called Biotech Success Stories with entries on GILD and Genentech.] ----------------------------------------------------------------------------------------------- Musings on the State of Biotech, Big Pharma, and Healthcare Costs The Numbers Game of Drug Development (a simple chart from the US federal government): <a href='read_msg.aspx?message_id=37325683'>#msg-37325683</a> Why Does US Healthcare Cost So Much? (a blog from The Atlantic) <a href='read_msg.aspx?message_id=36993611'>#msg-36993611</a> The Real Story Behind Spiraling Healthcare Costs (New Yorker magazine) <a href='read_msg.aspx?message_id=7878620'>#msg-7878620</a> Healthcare Spending vs GDP A picture worth a thousand words: <a href='read_msg.aspx?message_id=27114485'>#msg-27114485</a> Healthcare and the R Word (‘R’ stands for rationing) <a href='read_msg.aspx?message_id=18495262'>#msg-18495262</a> Patently Absurd Musings from The Economist on the KSR patent case: <a href='read_msg.aspx?message_id=19404785'>#msg-19404785</a> (article) <a href='read_msg.aspx?message_id=37325719'>#msg-37325719</a> (chart) Reinventing Big Pharma (Forbes) <a href='read_msg.aspx?message_id=8708384'>#msg-8708384</a> What’s Wrong with the War On Cancer (Boston Globe) <a href='read_msg.aspx?message_id=24966877'>#msg-24966877</a> ----------------------------------------------------------------------------------------------- Biotech Success Stories The Profit Pill A short history of Gilead from Forbes: <a href='read_msg.aspx?message_id=36507844'>#msg-36507844</a> A Tribute to Genentech Company highlights 1976-2009: <a href='read_msg.aspx?message_id=36635611'>#msg-36635611</a> ----------------------------------------------------------------------------------------------- Pitfalls of Biotech Investing Program-Survival Bias (Journal of Clinical Oncology) <a href='read_msg.aspx?message_id=7959424'>#msg-7959424</a> The Challenge of Subgroup Analysis (NEJM) <a href='read_msg.aspx?message_id=10754654'>#msg-10754654</a> Too many cancer drugs chasing too few reimbursement dollars: <a href='read_msg.aspx?message_id=11432606'>#msg-11432606</a> Zebra’s Law <a href='read_msg.aspx?message_id=23784371'>#msg-23784371</a> ----------------------------------------------------------------------------------------------- Let’s Talk Science How RNAi Works (Video from PBS/Nova) <a href='read_msg.aspx?message_id=9675929'>#msg-9675929</a> [The next two items are best read as a set.] Stem Cells: the Real Culprits in Cancer? (Scientific American) <a href='read_msg.aspx?message_id=11785699'>#msg-11785699</a> Scientists Weigh Stem Cells’ Role as Cancer’s Cause (NY Times) <a href='read_msg.aspx?message_id=25479450'>#msg-25479450</a> Immune System Revived to Fight Deadliest Diseases (Wall Street Journal) <a href='read_msg.aspx?message_id=12795650'>#msg-12795650</a> The Tumor That Isn’t: Blocking a Path to Cancer (NY Times) <a href='read_msg.aspx?message_id=13400473'>#msg-13400473</a> Decoding Alzheimer's (Business Week) <a href='read_msg.aspx?message_id=15892303'>#msg-15892303</a> ----------------------------------------------------------------------------------------------- Arrogance, Greed, and Corruption Mary Meeker’s Fuzzy Math (Wall Street Journal) <a href='read_msg.aspx?message_id=22503208'>#msg-22503208</a> Doctors Reveal Confidential Clinical Data for the Right Price (Seattle Times) <a href='read_msg.aspx?message_id=7263103'>#msg-7263103</a> Most Science is Tainted (Wall Street Journal) <a href='read_msg.aspx?message_id=22859747'>#msg-22859747</a> Is Your CEO Lying? (Barron’s) <a href='read_msg.aspx?message_id=11961951'>#msg-11961951</a> ----------------------------------------------------------------------------------------------- Miscellaneous <img src=http://208.78.96.220/bar-headed_goose.jpg> Bar-Headed Geese Migrate Over Mt Everest, Where Oxygen Is Scarce and Life Is Rare <a href='read_msg.aspx?message_id=8427157'>#msg-8427157</a>