Whether hepatitis C virus will develop resistance to VX-950 or other protease inhibitors isn't known… if the drug keeps viral levels low, there's a good chance the virus won't become resistant. It's even possible, Schiff says, that hepatitis C protease inhibitors will work all by themselves, without the need for combination therapy.
That an expert in the field said this as recently as 2005 shows how rapidly this field has evolved.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”