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ghmm

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ghmm

Re: ThomasS post# 76358

Tuesday, 04/21/2009 10:03:10 PM

Tuesday, April 21, 2009 10:03:10 PM

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INFORM:

What I was impressed with is they jumped right up to the 600mg and 900mg 191 (BID) doses. To me this means they saw little to no drug interaction that they feel confident enough to jump right to the highest doses used in the 1B.

I just looked up the 191 monotherapy results (#msg-33270341) and in the NR cohort 300mg BID had a 2.5 log drop.

EDIT:
Here is the link to the clinicaltrials record for those interested (didn't see anything not mentioned in ITMN's PR).
http://clinicaltrials.gov/ct2/show/NCT00801255
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