Most toxicity issues show up in phase-2 when a new drug is combined with other treatments and is tested for 4 weeks or longer.
Thanks Dew, very helpful. It appears that based on the existing Phase 1 results, R7128 safety data has been comparable to placebo up to 4 weeks in combination with SoC. You summarized those results here: http://investorshub.advfn.com/boards/replies.aspx?msg=31999860
We'll see how the drug fares beyond 4 weeks in the upcoming Phase 2b. But, so far so good.