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genisi

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genisi

Re: DewDiligence post# 75493

Saturday, 04/04/2009 3:53:40 PM

Saturday, April 04, 2009 3:53:40 PM

Post# of 257262
Clevudine does have a different MoA cause it primarily acts by blocking the HBV polymerase enzyme from incorporating nucleosides into a new viral DNA chain, whereas other antiviral agents compete with natural nucleosides for building HBV NDA chain and cause termination of the viral DNA.
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