Biotech Values

[poorgradstudent]

>I guess your supposition just didn't make any sense to me because TELK's drug was nothing like Thresholds aside from they were both using a prodrug that after its metabalized was an alkylator.... I can't say what Telcyta was metabalized into, but TH-302 prodrug is a phosphoramidate-based, DNA-crosslinking, bis-alkylator mustard...<

Bingo! Telcyta's active moiety was a phosphoramidate, just like TH-302.

In other words, the active versions of Telcyta and TH-302 (following cleavage of the pro-drug) are practically identical!