This is essentially the idea that OXGN touted several years ago for combination treatment with Avastin + Zybrestat (f/k/a/ CA4P), but I don’t think it amounted to a hill of beans
You get it all wrong Dew, the MOA of zybrestat and TH-302 is not the same. There is clear evidence that zybrestat and avastin has a synergistic effect but they are essentially both attacking the blood supply. I would think that TH-302 could be used with both avastin and zybrestat and, who knows perhaps the three of them could be combined. I will put Treshold on my watch list. TH-302 looks like an interesting substance!