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Re: ghmm post# 73881

Tuesday, 03/03/2009 6:37:14 PM

Tuesday, March 03, 2009 6:37:14 PM

Post# of 257257
Re: VRTX IDIX ANDS / non-nuke polymerase inhibitors

VRTX is playing is cards close to the vest on the acquired molecules, but on today’s CC Kurt Graves let on that VCH-222, the lead ViroChem compound, binds to the “thumb” site on the HCV polymerase. This distinguishes VCH-222 from ANA598 and IDX375, which bind to the “palm” site.


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