40M-60M royalties from Recothrom EU sales (2014 maybe).
2B sales of interferon lambda (give it a 5% success chance)
500M sales of Atacicpet in both RA and SLE indications (say a 15% success chance).
IL-21 can be a big big drug if cancer vaccines show survival benefits. They have showed that IL-21 can boost the effect of cancer vaccines in animal models. IL-2 has sales around 100M so lets assume peak sales of IL-21 is around 100M for now.