UTHR FREEDOM-M study: As I have posted (on the PLX board), having 21 extra patients seemed too little to me. Adding 100 more, so the majority (~150) of patients will have access to the 0.25mg pill, makes a p-value of 0.01 in this trial achievable, imo. On MS, this one has a summery: <a href="http://emedicine.medscape.com/article/1146199-treatment" target="_blank">http://emedicine.medscape.com/article/1146199-treatment</a>