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Re: DewDiligence post# 69495

Thursday, 12/04/2008 9:36:54 PM

Thursday, December 04, 2008 9:36:54 PM

Post# of 252807
It’s either a typo or sloppy English in omitting the second instance of the word median.

It's the language within the PR, moreso than the headline itself, that I think may be more revealing. The fact that they do not refer to the control arm along with the OGX-011 arm when noting the need for more survival updates to calculate median survival is what leads me to think maybe all events have in fact occurred in the control arm.

Overall survival per se cannot be stated as a unit of time—it must be stated as a ratio relative to the overall survival of a different trial arm.

I think they make the distinction in the PR between overall survival, where we know there is a 40% lower rate for the OGX-011 arm, and the current median survival time in months. Based on what I quoted before, assuming all events have occurred in the control arm, that median survival time in months in the control arm is 16.9 months.
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