Biotech Values

[mcbio]

? Not sure what you are asking different than I already expressed. If HR=0.60 on a trial with 40 patients per arm then only a small percentage of patients could have died so far. As a greater percentage die the HR and the p value will change.

Ok thanks, I was just trying to ensure that I understood your point and I do.

The more interesting point is that they gave enough data to hint that the HR through, say, 20 months was a lot better than 0.60.

But again, that really doesn't mean much if you don't also get a p value <.05 does it? And it doesn't seem like we have any way of knowing the p value given the data we have so far. Are there instances where hazard ratios still matter even if p value >.05?