Welch has always struck me as a straight shooter. Was he crossed up by Roche, or did he simply misinterpret the question about the INFORM-1 design on the recent webcast?
But he also is very careful in disclosing information (as Adam Feurestein can attest to in his prejudging mean vs. median data). On roche matters he's often spoken in generalizations giving an idea but not specifics. What I do recall is him saying at the Deutche Bank Confab is to do kind of a matrix lo/lo, lo/hi, hi/lo, hi/hi which i don't see in this design. But he may have been trying to limit what was disclosed as he was not giving specific trial design.