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Re: DewDiligence post# 69422

Wednesday, 12/03/2008 6:49:51 PM

Wednesday, December 03, 2008 6:49:51 PM

Post# of 257275
An approximately 40% lower death rate means the HR is ~0.60 based on the events observed to date.

I knew of the "death rate appox 40% lower..." in the PR and I completely agree that your interpretation is *probably* correct. I am poking at the fact that I have to caveat it with *probably* since they used the word 'approximately' and they did not talk of "HR". I have been tricked before when companies were, for instance, refering to a landmark analysis when talking of death rate reductions.

i.e. I was making a minor point - and a note to myself that I need to check it when the data comes out in its entirety.


PS My WAG is that if you calculated p value out of 20 months on their current results that the p value would be very low indeed (p~0.001 or less). And if the remaining patients continue the same curve the p value out of 20 months or so will be spectacular. I.e. my guess is the stuff works, albeit possibly with some PSB discount necessary.

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